Immunological Approach of Personalized Treatment for Recurrent Implantation Failure Patients Undergoing IVF

Onm-8: Recurrent Implantation Failure in IVF/ICSI Cycle

The success of assisted reproduction, although gradually increasing over the years, is still less than satisfactory. Many couples have benefited from this treatment; many have also been left frustrated following multiple failed attempts (Bulent Urman et al. 2005). Repeated implantation failure (RIF), defined as three or more failed IVF attempts or failure of IVF after cumula- Abstracts of the 5...

I-24: Recurrent Implantation Failure

Recurrent implantation failure (RIF) has many definitions, but usually authors consider RIF, the failure to achieve a pregnancy fallowing 2-6 IVF cycles in which more than 10 high grade embryos were transferred to the uterus. There are a lot of causes for RIF but two main causes of that are related to embryo and endometrium. Chromosomal abnormalities, zona hardening and problems in culture medi...

I-16: The Immunological Aspect of Implantation Failure

The success of reproduction, although gradually increasing over the years, many couples also had been left frustrated following repeated failed attempts. Clinicians who treated unsuccessful couples often face a challenge. The probable causes of repeated IVF failures classified as: reduced endometrial receptivity, embryonic defects or multifactorial causes. Intrauterine and endometrial integrity...

Reduced plasma fibrinolytic potential in patients with recurrent implantation failure after IVF and embryo transfer.

BACKGROUND Recurrent implantation failure (RIF) following embryo transfer (ET) is a major continuing problem in IVF. Women with haemostatic defects may be at increased risk of miscarriage and preclinical pregnancy loss. The fibrinolytic system is considered, at present, the key to new thrombotic pathogenic mechanisms. Patients with unexplained recurrent miscarriage have an impairment of fibrino...

Recurrent Implantation Failure Is More Frequently Seen in Female Patients with Poor Prognosis